P-Hydroxybenzoic acid | MMP-AC0210

	Compound Name :	P-Hydroxybenzoic acid
	Compound Class :	Simple aromatic natural product
	Synonyms :	4-hydroxybenzoate; 4-hydroxybenzoic acid; 4-hydroxybenzoic acid; calcium salt; 4-hydroxybenzoic acid;
	Compound Extracted from :	P-Hydroxybenzoic acid is extracted / reported from 2 Plant(s) of Melghat Flora as below MH061: Psoralea corylifolia L.; MS003: Capparis zeylanica L.;

	Molecular Formula :	C7H6O3
	Molecular Weight :	138.12
	InChi Key :	FJKROLUGYXJWQN-UHFFFAOYSA-N
	IUPAC :	4-hydroxybenzoic acid
	InChi :	InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)
	Hydrogen Bond Donor count :	2
	Hydrogen Bond Acceptor count :	3
	Rotational Bond count :	1
	TPSA :	57.5
	LogP Value :	1.6

	Lipinski Rule of Five :	Yes
	Ghose Filter :	No
	Veber Filter :	Yes
	Muegge Filter :	No

	PubChem CID :	135
	Drugbank ID :	DB04242
	Super Natural :	000099967
	CTD :	-
	HIT :	-
	NCI-60 GI50 data :	-

	Reference(s) :	https://pubchem.ncbi.nlm.nih.gov/compound/135

Compound_ID	Cell Lines	Cancer Type	IC50 Value	EC50 Value	ED50 Value	GI50 Value	References
MMP-AC0210	MCF-7	Breast	-	>1000 然	-	-	16968064
MMP-AC0210	Hep G2	Liver	-	>1000 然	-	-	16968064

Compound_ID	Target	Gene_Name	Gene_ID	Cancer	Cell_lines	IC50 Value	EC50 Value	ED50 Value	GI50 Value	Remarks	References
MMP-AC0210	SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	6818	Hepatoma	Hep G2	-	-	-	-	p-hydroxybenzoic acid was found to increase PST-P activity. p-hydroxybenzoic acid showed a moderate increase of PST-P activity at concentrations of 10-50 然, with a maximum of 2-2.5-fold.	15941313

MMP-AC0210 : P-Hydroxybenzoic acid