Inhibition rate of 52.8% was observed in tumor growth in Ursolic acid treated xenografts. The result of western blot showed that the protein level of Caspase-3 was elevated after treatment with UA
Inhibition rate of 52.8% was observed in tumor growth in Ursolic acid treated xenografts. The result of western blot showed that the protein level of Caspase-8 was elevated after treatment with UA
PTP1B is overexpressed in human breast cancer, and inhibition of PTP1B delays erbB2-induced mammary tumorigenesis and protects from lung metastasis.Among the isolated compounds, erystgallin A along with isolated compounds was evaluated for their inhibitory effects on protein tyrosine phosphatase-1B (PTP1B), as well as their growth inhibition on MCF7.