Botanical Name Plant's Common Name Plant Family   

   MMP-AC0122 : Terpinolene

 
Compound Name  :

Terpinolene
 
  Compound Class  : Terpenoids  
  Synonyms  : TERPINOLENE; 586-62-9; Isoterpinene; Terpinolen; alpha-Terpinolene;

 
  Compound Extracted from  : Terpinolene is extracted / reported from 5 Plant(s) of Melghat Flora as below


 
 
Molecular Formula  :

C10H16
 
  Molecular Weight  : 136.23  
  InChi Key  :  
  IUPAC  :  
  InChi  :  
  Hydrogen Bond Donor count  : 0  
  Hydrogen Bond Acceptor count  : 0  
  Rotational Bond count  : 0  
  TPSA  : 0  
  LogP Value  :

2.8

 
 
Lipinski Rule of Five  :

Yes
 
  Ghose Filter  : No  
  Veber Filter  : Yes  
  Muegge Filter  :

No

 
 
PubChem CID  :

11463
 
  Drugbank ID  : -  
  Super Natural  : 000586629  
  CTD  : C027009  
  HIT  : -  
  NCI-60 GI50 data  :

-

 
 
Reference(s)  :

https://www.ncbi.nlm.nih.gov/pubmed/22740904


 

Compound_ID Cell Lines Cancer Type IC50 Value EC50 Value ED50 Value GI50 Value References
MMP-AC0122 MCF-7 Breast - - - >250 µM 12802719

Compound_ID Target Gene_Name Gene_ID Cancer Cell_lines IC50 Value EC50 Value ED50 Value GI50 Value Remarks References
MMP-AC0122 AKT1 v-akt murine thymoma viral oncogene homolog 1 207 - K-562 - - - - the protein expression of AKT1 was decreased with the increasing concentrations of terpinolene in the K562 and Jurkat cells 22740904
MMP-AC0122 AKT1 v-akt murine thymoma viral oncogene homolog 1 207 - Jurkat - - - - the protein expression of AKT1 was decreased with the increasing concentrations of terpinolene in the K562 and Jurkat cells 22740904