Botanical Name Plant's Common Name Plant Family   

   MMP-AC0123 : Perillaldehyde

 
Compound Name  :

Perillaldehyde
 
  Compound Class  : Terpenoids  
  Synonyms  : PERILLALDEHYDE; Perillyl aldehyde; Perilla aldehyde; Perillal; 2111-75-3;

 
  Compound Extracted from  : Perillaldehyde is extracted / reported from 1 Plant(s) of Melghat Flora as below


 
 
Molecular Formula  :

C10H14O
 
  Molecular Weight  : 150.22  
  InChi Key  :  
  IUPAC  :  
  InChi  :  
  Hydrogen Bond Donor count  : 0  
  Hydrogen Bond Acceptor count  : 1  
  Rotational Bond count  : 2  
  TPSA  : 17.1  
  LogP Value  :

2.6

 
 
Lipinski Rule of Five  :

Yes
 
  Ghose Filter  : No  
  Veber Filter  : Yes  
  Muegge Filter  :

No

 
 
PubChem CID  :

16441
 
  Drugbank ID  : -  
  Super Natural  : -  
  CTD  : C033342  
  HIT  : -  
  NCI-60 GI50 data  :

-

 
 
Reference(s)  :

https://www.ncbi.nlm.nih.gov/pubmed/21580329


 

Compound_ID Cell Lines Cancer Type IC50 Value EC50 Value ED50 Value GI50 Value References
MMP-AC0123 B16(F10) Skin 120±17 µMol/L - - - 9164984

Compound_ID Target Gene_Name Gene_ID Cancer Cell_lines IC50 Value EC50 Value ED50 Value GI50 Value Remarks References
MMP-AC0123 RAP1A RAP1A, member of RAS oncogene family 5906 Leukemia K-562 - - - - Perillaldehyde was found to decrease the up-regulation of Rap1a induced by mevalonate depletion 12671036
MMP-AC0123 RHOA ras homolog family member A 387 Leukemia K-562 - - - - Perillaldehyde was found to decrease the up-regulation of RhoA induced by mevalonate depletion 12671036
MMP-AC0123 RHOB ras homolog family member B 388 Leukemia K-562 - - - - Perillaldehyde was found to decrease the up-regulation of RhoB induced by mevalonate depletion 12671036